Bisphosphonates such as Fosamax and Actonel are used to strengthen bones in which condition?

• A. Osteoporosis
• B. Osteoarthritis
• C. Gout
• D. Tendinopathy

Answer: (A)

Bisphosphonates work by slowing bone breakdown. They inhibit osteoclasts, the cells responsible for resorbing bone, which decreases bone turnover and helps increase bone density. In osteoporosis, bones become porous and fragile, so strengthening them reduces fracture risk. These drugs aren’t used for conditions like osteoarthritis, gout, or tendinopathy, which involve joints, crystals, or tendons rather than bone loss. Fosamax and Actonel are examples given for osteoporosis management.